Mechanisms of COX2 regulation and prostanoid pathway
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چکیده
THE LANCET Oncology Vol 4 October 2003 http://image.thelancet.com/extras/03oncl205webfr.pdf
منابع مشابه
Differentiation of cyclooxygenase 1- and 2-derived prostanoids in mouse kidney and aorta.
Accumulating evidence indicates cyclooxygenase (COX) 1 and COX2 differentially regulate cardiovascular and renal function. We have demonstrated previously in mice that COX2 inhibition enhances angiotensin II-induced hypertension, and COX1 inhibition attenuates the pressor effect of angiotensin II. To further elucidate the mechanism underlying the functional difference of COX1 versus COX2 inhibi...
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